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2.24 Specimen requirements
Written by Pathology Manager   

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Adult Reference and therapeutic drug ranges

Test Specimen & tube Reference and therapeutic ranges (Adults) Comments (reporting frequency)
ACTH EDTA (lavender) See report for Interpretation Contact lab. Sample to lab on ice within 10 mins of collection. 2-3 weeks
Alanine transaminase (ALT) Serum (gold) 0 – 60 IU/L Urgent/daily
Albumin Serum (gold) 32 – 50 g/L Urgent/daily
Albumin (urine) 24 hr urine 0 – 300 mg/24 hr Daily
Albumin/creat ratio (urine) EMU < 2.5 mg/mmol M
< 3.5 mg/mmol F
Daily
Aldosterone Heparin (green) See report for Interpretation Contact lab. Sample to lab within 10 mins of collection. 2-3 weeks
Alkaline Phosphatase (ALP) Serum (gold) 38-126 IU/L Urgent/daily
Alpha fetoprotein (AFP) Serum (gold) See report Weekly
Amino acids (plasma) Heparin (green) Normal pattern 2-3 weeks
Amino acids (urine) Random urine Normal pattern 2-3 weeks
Ammonia (plasma) Heparin (green) See report for Interpretation Contact lab. Sample to lab within 20 mins of collection. Urgent/daily
Amylase Serum (gold) 30-110 IU/L Urgent/daily
Androstenedione Serum (gold) See report 2-3 weeks
Angiotensin Converting Enzyme Serum (gold) 8-52 IU/L 2-3 weeks
Aspartate transaminase (AST) Serum (gold) 0-60 IU/L M 0-40 IU/L F Urgent/daily
Bence Jones Protein (BJP) Early Morning Urine N/A Weekly
Bicarbonate Serum (gold) 22-31 mmol/L Urgent/daily
Bilirubin (total) Serum (gold) 1-22 μmol/L Urgent/daily
Bilirubin (conjugated) Serum (gold) 0-5 μmol/L Urgent/daily
BNP EDTA (lavender) 0-100 ng/L Weekly
Ca125 Serum (gold) 0-23 KU/L Daily
Ca15-3 Serum (gold) 0-25 KU/L Daily
Ca19-9 Serum (gold) 0-33 KU/L Daily
Caeruloplasmin Serum (gold) 0.20-0.60 g/L 2-3 weeks
Calcitonin Serum (gold) 0 – 18.9 ng/L M
0 - 5.5 ng/L F
Contact lab.
Sample to lab on ice within 10 mins of collection. 2-3 weeks
Calcium Serum (gold) 2.10 – 2.60 mmol/L Urgent/daily
Calcium (urine) 24 hour urine 2.5 – 7.5 mmol/24 hr Daily
Carbamazepine Serum (gold) 17 – 50 μmol/L (single therapy) Sample should be pre-dose. Urgent/daily
Carcinoembryonic Antigen (CEA) Serum (gold) 0 – 4 μg/L Daily
Catecholamines (urine) 24 hour urine Noradrenaline < 500 nmol/24 hr
Adrenaline <100 nmol/24 hr
Dopamine <3000 nmol/24 hr
Supply current drug therapy. 2-3 weeks
Chloride (Serum) Serum (gold) 95-106 mmol/L Urgent/daily
Chloride (Sweat) By prior arrangement See report Contact lab Ext. 3040 / 3042. By prior arrangement
Cholesterol (total) Serum (gold) 3.8-5.2 mmol/L (desirable range) Daily
Cortisol (serum) Serum (gold) See report for Interpretation Daily
Complement (C3/C4) Serum (gold) or EDTA (lavender) C3 0.9-1.7 g/L
C4 0.12-0.36 g/L
Weekly
Copper Serum (gold) 11-20 μmol/L 2-3 weeks
Copper (urine) 24 hour urine in acid washed container < 0.9 μmol/24 hr Contact lab. Acid washed container required.
Cortisol (urine) 24 hour urine 50-270 nmol/24 hr 2-3 weeks
C-peptide Serum (gold) See report for interpretation Contact lab. Sample to lab within 2 hr of collection. 2-3 weeks
C-reactive protein (CRP) Serum (gold) 0- 5 mg/L (adult) Urgent/daily
Creatine Kinase (CK) Serum (gold) 55-170 IU/L M
30-135 IU/L F
Urgent/daily
Chromosomes Heparin (green)
If Fragile X required an EDTA (purple tube) must also be taken
See report Contact lab. By prior arrangement. Samples only accepted Monday,Tuesday, Wednesday.
Creatinine Serum (gold) 40-120 μmol/L Urgent/daily
Creatinine (urine) 24 hour urine 9-17 mmol/24 hr Daily
Creatinine clearance Serum (gold) + 24 hour urine 60-130 ml/min Daily
Cryoglobulins Serum (gold) and EDTA (lavender) Not detected Contact lab. Samples must be collected at 370C and brought to lab immediately. Collection on SPH site only.
Cystine screen Random urine Not detected 2-3 weeks
DHEAS Serum (gold) See report 2-3 weeks
Digoxin Serum (gold) 0.9 – 2.6 nmol/L (6 hrs post dose) Urgent/daily
Drug screen (toxicology/overdose) Urine and serum   By arrangement.
Drugs of abuse screen Random urine Negative Weekly
eGFR Serum (gold) >60ml/min (Adults) Urgent/daily
Elastase (faeces) Random faeces > 200 mg/1g faeces 2-3 weeks
Ferritin Serum (gold) 15-300 μg/L Daily
FSH Serum (gold) See report Daily
Free T3 Serum (gold) 2.8 – 6.5 pmol/L Daily
Free T4 Serum (gold) 9-24 pmol/L Daily
Free Testosterone Index (Free Androgen Index) Serum (gold) 1.0-5.5 F
30-100 M
2 weeks
Gamma-GT Serum (gold) 0-60 IU/L M
0-50 IU/L F
Daily
Gastrin (fasting) 2 pre-chilled EDTA tubes transported immediately to the lab on iced water < 40 pmol/L (fasting) Contact lab. Fasting sample 2-3 weeks
Gases :
pH
pCO2
pO2
Arterial blood  
7.38 – 7.42
4.5 – 6.1 Kpa
12 – 15 Kpa
No analyser in lab. Analysers sited in A&E, ITU and NICU, MAU,MHDU, Labour Ward (SPH) Wordsworth and RAC (ASH)
Glucose (plasma) Fluoride (grey) 3-6 mmol/L (fasting)
3-11 mmol/L (random)
Urgent/daily
Glucose (CSF) CSF (grey) Relates to plasma glucose (normal approx. 2/3 plasma value) Urgent/daily
Growth hormone Serum (gold) See report 1-2 weeks
Gut hormone profile:
VIP profile
PP
Gastrin
Glucagon
Neurotensin
.2 pre-chilled EDTA tubes transported immediately to the lab on iced water  
< 30 pmol/L
< 300 pmol/L
< 40 pmol/L
< 50 pmol/L
<100 pmol/L
Contact lab. Special heparin tube with trasylol required. Sample to lab within 5 minutes. 2-3 weeks
HbA1c Whole blood EDTA (lavender) 4.8 – 6.0 % Daily
HDL cholesterol Serum (gold) 1.0–2.0 mmol/L M
1.3-2.3 mmol/L F
Daily
HCG Serum (gold) 0-4 IU/L Urgent/daily
5-HIAA (urine) 24 hour urine 5-52 μmol/24 hr 2-3 weeks
IGF-1 Serum (gold) See report 2-3 weeks
Immunoglobulins Serum (gold) See report Daily
Insulin Serum (gold) See report Contact lab. Sample to lab within 2 hrs of collection. 2-3 weeks
Iron Serum (gold) 8.8-32.4 μmol/L M
6.6-30.4 μmol/L F
Urgent/daily
Iron Binding Capacity(IBC)
% Iron saturation
Serum (gold) 44.8 – 80.6 μmol/L
20 – 55%
Daily
Lactate Fluoride (grey) 0.7-2.1 mmol/L Test available on blood gas analysers (ITU & NICU A&E, MAU, MHDU (SPH) Wordswoth & RAC (ASH). Contact lab. Take sample & ensure arrival in lab within 1hr of collection Urgent/daily
Lactate: Pyruvate ratio By special arrangement only (Contact lab.) See report By special arrangement. Contact lab.
Lactate Dehydrogenase LDH Serum (gold) 266-500 IU/L Urgent/daily
LDL (calculated) Serum (gold) (fasting) 2.3 – 3.4 mmol/L (desirable) Daily
Lead Whole blood (lavender) EDTA < 0.5 μmol/L 2-3 weeks
Lithium Serum (gold) 0.4-1.0 mmol/L Sample should be 12 hrs post dose. Urgent/daily
LH Serum (gold) See report Daily
Magnesium Serum (gold) 0.65-1.0 mmol/L Urgent/daily
Metanephrine (urine) 24 hour urine Normetadrenaline 0-3.3umol/day
Metadrenaline 0-1.2umol/day
3-methoxytryptamine 0-2.5μmol/day
Supply current drug therapy. 2-3 weeks
Occult Blood (faecal) Random faeces Negative Daily
Oestradiol Serum (gold) See report Daily
Organic acids (urine) Random urine Normal pattern 2-3 weeks
Osmolality Serum (gold) 275-295 mmol/kg Urgent/daily
Osmolality (urine) Random urine 60-1500 mmol/kg Urgent/daily
Paracetamol Serum (gold) Not detected. Refer to A & E for treatment guidelines. Urgent/daily
Parathyroid Hormone EDTA (lavender) See report Sample should arrive in lab within 6 hr of collection. Weekly
Phenobarbitone Serum (gold) 0-30 mg/L up to 1 months
0-40mg/L >1 month and adults
Take sample immediately before next dose. Weekly
Phenytoin Serum (gold) 40-80 μmol/L Take sample immediately before next dose. Urgent/daily
Phosphate Serum (gold) 0.8-1.4 mmol/L (adult) Urgent/daily
Phosphate (urine) 24 hr urine 15-50 mmol/24 hr Daily
PBG (urine) Random urine
Protect from light
Not detected Contact lab Urgent/daily
Porphyrin (faeces) Faeces
Protect from light
See report Contact lab. 2-3 weeks
Porphyrin (urine) Random urine
Protect from light
Within normal limits Contact lab. Urgent/daily
Porphyrin (whole blood) Whole blood EDTA (lavender)
Protect from light
See report Contact lab. 2-3 weeks
Potassium Serum (gold) 3.5 – 5.0 mmol/L Urgent/daily
Potassium (urine) 24 hr/random 35-90 mmol/24 hr Urgent/daily
Progesterone Serum (gold) See report Daily
Prolactin Serum (gold) 45-375 mU/L M
59-620 mU/L F
Daily
Prostate specific antigen (PSA) Serum (gold) Males
< 50
< 2.5 μg/L 50-59
< 3.5 μg/L 60-69
< 4.5 μg/L
70 + < 6.5 μg/L
Daily
Protein (serum total) Serum (gold) 60-84 g/L Daily
Protein (urine) Random urine
24 hour urine
< 0.1 g/L
< 0.15 g/24 hr
Daily
Protein (CSF) CSF 0.1-0.4 g/L (adult) Urgent/daily
Protein electrophoresis Serum (gold) Within normal limits To exclude myeloma both serum and urine are required.
Reducing substances (faecal) Fresh faeces sent to lab within 20 minutes. Not detected. Contact lab. Sample must reach lab within 20 minutes. Urgent/daily
Reducing substances (urine) Fresh random urine Not detected. Sample must reach lab within 4 hours. Urgent/daily
Renin Heparin (green-adults) See report for Interpretation Contact lab. Sample to lab within 10 mins of collection. NOT on ice 2-3 weeks
Salicylate Serum (gold) Not detected Urgent/daily
Selenium Trace Metals tube (blue) 0.89-1.65 μmol/L (adult) 2-3 weeks
SHBG Serum (gold) 15-55 nmol/L M
30-100 nmol/L F
2 weeks
Sodium Serum (gold) 133-147 mmol/L Urgent/daily
Sodium (sweat) By prior arrangement. See report Contact lab. Ext. 3040/3042 By prior arrangement.
Sodium (urine) 24 hr urine or random 40-220 mmol/24 hour Urgent/daily
Steroid profile (urine) 24 hr urine See report 2-3 weeks
Sugar chromatography (faecal) Fresh faeces sent to lab within 20 mins. See report Contact lab. Sample must reach lab within 20 mins. Weekly
Sugar chromatography (urine) Fresh urine See report Contact lab. Sample must reach lab. within 4 hrs. Urgent/daily by arrangement.
Testosterone Serum (gold) 10-30 nmol/L M
0-3 nmol/L F
Daily
Theophylline Serum (gold) 55-110 μmol/L (adult) Take sample immediately before next dose. Urgent/daily
TSH Serum (gold) 0.35-5.0 mU/L Daily
Triglycerides (fasting) Serum (gold) fasting 0.8-2.0 mmol/L (fasting) Daily
Troponin I Serum (gold) 0-0.1 μg/L Urgent/daily
Urea Serum (gold) 2.5-6.5 mmol/L
< 65yr 4.0-10.0 mmol/L > 65yr
Urgent/daily
Urea (urine) 24 hr /random urine 166-581 mmol/24 hr Daily
Uric acid Serum (gold) 200-500 μmol/L M
150-450 μmol/L F
Urgent/daily
Uric acid (urine) 24 hr urine 3-12 mmol/24 hr Daily
Valproate Serum (gold) 350-700 μmol/L (adults) Take sample immediately before next dose.Urgent/daily
Vitamin D (25 OHy vitamin D) Serum (gold) See report 2-3 weeks
VMA (HMMA) See Catecholamines  
White Cell Enzymes Whole blood Heparin (green) See report Specify the enzyme analysis required. 3-4 weeks
Zinc Serum (gold) or Trace metals tube(blue) 11-24 μmol/L 2 weeks


Time limits for requesting additional investigations

Biochemistry: 4 days for all tests apart from Potassium, Bicarbonate and phosphate

Also see information under sample collection requirements.

 

Last Updated ( Monday, 04 July 2011 14:36 )